KP-TNC works with the following key population topologies:

PWID

People who inject drugs (PWID) refers to individuals who introduce psychoactive substances into their bodies via injection, a behavior carrying significant health risks. This makes PWID a “key population” for public health interventions, particularly regarding HIV, viral hepatitis, and overdose prevention. Beyond the act of injection, PWID often experiences a complex interplay of vulnerabilities, including increased risk of infectious diseases, overdose, mental health challenges, social marginalization, healthcare inequities, human rights violations, and exclusion from policy discourse. 

The sustainability of programs supporting PWIDs is threatened by funding challenges, such as the current withdrawal of PEPFAR support. Addressing this and other systemic issues requires a rights-based approach that prioritizes inclusivity, equity, and long-term solutions for this vulnerable group.

The World Health Organization (WHO) advocates for comprehensive harm reduction strategies for PWID, including needle and syringe programs (NSPs), opioid substitution therapy (OST), access to naloxone, and integrated healthcare services. This approach aims to minimize the negative health and social consequences associated with drug injection and promote the well-being of PWID, recognizing their right to health and dignity.

Sex Workers

Sex workers, encompassing female, male, and transgender individuals who engage in sexual activities for compensation, are recognized as a “key population” by the WHO and UNAIDS. This categorization underscores their heightened vulnerability to specific health risks, including sexually transmitted infections (STIs), HIV, and violence. Consequently, public health interventions prioritize tailored services such as condom distribution, STI screening, and HIV prevention programs. Beyond healthcare, the WHO advocates for the empowerment of sex workers through the promotion of their rights, safety, and inclusion in health policies and programs, acknowledging the unique challenges they face.

Sex workers encounter a multitude of challenges beyond immediate health concerns, including significant mental health burdens, pervasive stigma and discrimination within both public and healthcare settings, limited access to contraception, and frequent human rights violations. They are also subject to physical and digital violence, further compounding their vulnerability. 

Moreover, programs designed to serve sex workers face significant sustainability challenges, particularly in the face of current funding changes such as the PEPFAR freeze, hindering the continuity of vital services and support.

Men who have sex with Men

Men who have sex with men (MSM) comprise a diverse group of individuals engaging in sexual activity with other men, irrespective of self-identified sexual orientation. This inclusive definition is fundamental to effective public health strategies, ensuring outreach to all at-risk individuals. The categorization of MSM as a “key population” underscores their disproportionate vulnerability to critical health challenges, notably HIV, sexually transmitted infections (STIs), and other health disparities stemming from social and systemic inequities.

MSMs encounter a complex web of obstacles, including pervasive stigma, discrimination, and human rights violations within both public and healthcare spheres. These barriers manifest as mental health challenges, limited access to care for opportunistic infections, the absence of needs-based HIV differentiated service delivery (DSD), physical and digital bullying, exclusion from policy discourse, and a dearth of tailored programming. The impending reduction in foreign aid presents a substantial threat to the sustainability of MSM-focused programs, further exacerbating these existing vulnerabilities and hindering access to essential health services.

The World Health Organization (WHO) advocates for the creation of inclusive, non-discriminatory environments that safeguard the rights and dignity of MSM. Central to this approach is the integration of MSM-specific interventions into national and global health policies, ensuring sustainable and equitable access to healthcare. By prioritizing the reduction of stigma, the promotion of human rights, and the implementation of targeted health programs, the WHO aims to improve the overall health and well-being of this key population.

Transgender

Transgender individuals, encompassing a diverse spectrum of identities including transgender women, transgender men, and non-binary people, are those whose gender identity differs from their sex assigned at birth. Recognized as a “key population” within public health frameworks, transgender people experience heightened vulnerability to health disparities, notably HIV, mental health challenges, and systemic barriers to accessing appropriate healthcare. 

Transgender people confront a multitude of formidable obstacles, including pervasive stigma, discrimination, and systemic exclusion within healthcare and broader societal settings. These challenges manifest as mental health burdens, limited access to care for opportunistic diseases, a lack of needs-based HIV differentiated service delivery (DSD), insufficient gender-affirming care, human rights violations, physical and digital violence, and exclusion from policy discourse. Compounding these issues, recent funding withdrawals and hostile policy narratives pose significant threats to the sustainability of transgender-focused programs, jeopardizing access to essential services.

It is essential to integrate transgender-specific health interventions into national and global health agendas, ensuring sustainable and rights-based care. By prioritizing the inclusion of transgender individuals in the development and implementation of health policies and programs, we aim to dismantle health inequities and foster the overall well-being of this vital key population. This approach emphasizes the importance of respecting rights, and ensuring that transgender individuals are able to access healthcare that meets their specific needs.

Individuals within prisons and other closed settings

Individuals within prisons and other closed settings are those confined in environments where their freedom of movement is severely restricted, including prisons, detention centers, and psychiatric institutions. These settings are characterized by restricted movement, congregate living, and often, limited access to essential services. Recognized as a “key population” within public health frameworks, they face heightened vulnerability to health risks, notably infectious diseases like HIV, tuberculosis, and hepatitis, alongside significant mental health challenges due to the unique stressors of confinement.

People in closed settings encounter a multitude of obstacles, including systemic barriers to healthcare access, potential human rights violations, and limited access to preventive services. These challenges are compounded by factors such as overcrowding, inadequate sanitation, and a lack of specialized medical care. Moreover, the recent freeze or withdrawal of funding from international aid programs poses a significant threat to the sustainability of programs designed to serve these populations. This funding reduction directly impacts the availability of essential services, including HIV testing and treatment, harm reduction initiatives, and mental health support, further jeopardizing the health and well-being of those detained.

It is imperative to prioritize the health and human rights of individuals in closed settings by ensuring the integration of comprehensive health interventions into national and global health agendas. This includes advocating for the provision of equitable healthcare, the implementation of harm reduction strategies, and the creation of safe and humane environments. By addressing the unique needs of this key population, we can work towards dismantling health inequities and promoting the overall well-being of those who are confined.